The epidemiology of endometriosis is poorly known as the pathophysiology and diagnosis are unclear

As the diagnosis requires a laparoscopy, we only have data in women with pain and/or infertility. Endometriosis has been considered to be single disease defined as ‘endometrium like glands and stroma outside uterus’. However, subtle, typical, cystic ovarian deep endometriosis lesions should different pathologies which occur all combinations severities. All large datasets, especially those based on hospital discharge records, consider without taking into account severity. In particular, variable prevalence recognition of subtle is problematic. Reliable surgical are small series not permitting multivariate analysis. hereditary disease. The oxidative stress heavy menstrual bleeding retrograde menstruation an altered pelvic microbiome probably associated increasingly severe endometriosis. Whether increasing, or whether fat intake increased risk cardiovascular unclear.